Wednesday, November 17, 2010

Another note about blood thinners.

Here is a note about Warfarin from the Thrombosis Society of Canada:

For most indications for OVKAs, the optimal INR range is 2-3; the INR range for patients with a mechanical mitral valve is generally 2.5-3.5. Lower intensity warfarin (INR 1.5-2.0) has shown benefit over no anticoagulation in the prevention of venous thromboembolism in patients receiving chemotherapy for stage III-IV breast cancer, and , when compared with no treatment, for the prevention of recurrent venous thrombosis. However, when long-term anticoagulation with a target INR range of 1.5-2.0 was compared with the range of 2-3, the latter was more effective and as safe as the lower range.

Please note the inverse relationship between dosage and age--as one gets older, the dosage amounts usually go down because old people tend to have thicker blood, I guess. Not the matriarch. Her current INR range is 1.6-1.9, thus her dosage of Warfarin has to increase contrary to expectations; she is 99 and she takes the same dosage as someone in their fifties. I think the woman is healthy. Stroke really isn't a concern and yet, we must go to weekly blood clinics.

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